The ER has many complex proteins and so have a robust system for heat-shock protein assisted folding9/22/2023 ![]() Interestingly, cell stress may trigger HSP translocation following induction of expression, such as HSP10 which is mainly localised in the mitochondrial matrix under normal conditions but migrates to the cytosol in response to stress 4. ![]() Owing to their fundamental role in maintaining homeostasis, HSPs have been found to be expressed in most cell compartments to accomplish various functions ( Table 1) 1-9. HSPs belong to five main families according to their respective molecular weight and have distinct cellular localisations and proposed functions. Table 1: Summary table of the main families of heat shock proteins, their described cellular location and proposed functionĪmong the main molecular chaperones are HSPs upregulated in response to stress such as heat and play important physiological roles in normal and under systemic and cellular stress conditions 3.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |